It has been regarded as a manifestation of tuberculin hypersensitivity, a type of. Pdf erythema induratum of bazin eib is a tuberculid showing lobular. E definito passivo quando e causato da una stasi venosa. Erythema induratum of bazin presenting as peripheral neuropathy. However, the true origin of the disease is a subject of speculation and remains. Treatment with a standard fourdrug antituberculous regimen resulted in radiographic and clinical improvement.
Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower legs that, histopathologically, show a lobular panniculitis. Erythema induratum of bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women. Erythema induratum was first identified in 1861, by bazin, as a nodular eruption that occurred on the lower legs posterior face of young women with tuberculosis. In patients suspected to have en but with necrotizing vasculitis, the. Erythema induratum of bazin is a hypersensitivity reaction to the tubercle bacillus. Here are links to possibly useful sources of information about erythema induratum. The egitema study reported the clinical case of a patient with eib who, after tuberculosis treatment, evolved with adrenal insufficiency. Erythema induratum an overview sciencedirect topics. Tuberculosis remains a global disease burden, counting more than 9. Treatment of eib and other cases of nodular vasculitis should be directed at the underlying cause of the immune response. Erythema induratum oe bazin, international journal of.
Erythema induratum of bazin eib nodular vasculitis associated with mycobacterium tuberculosis tb and. Epidemiological, clinical and laboratorial profile of 54 patients. It is considered to be a hypersensitivity reaction to m. There is limited data and a lack of diagnostic and treatment standards for these conditions. Erythema induratum of bazin eib nodular vasculitis associated with mycobacterium tuberculosis tb and tuberculosisassociated ocular inflammation tbaoi represent uncommon manifestations of tb. Erythema induratum of bazin and poncets arthropathy. Erythema induratum is a panniculitis on the calves. Ideal sources for wikipedia s health content are defined in the guideline wikipedia. An 81yearold woman with a history of renal cell carcinoma and years of slowly, progressively enlarging pulmonary nodules of uncertain etiology presented with. Erythema induratum of bazin and poncets arthropathy as epiphenomena of hepatic tuberculosis. Simile ell eritema nodoso caratterizzata da noduli roseoviolacei, piani, duri, dolenti alla palpazione, sulla superficie esterna di braccia, superficie posteriore delle gambe, sulla fronte, piu frequente nelle giovani donne, ad evoluzione subacuta o cronica diagnosi differenziale con l eritema nodoso nell eritema induratum. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower. This case report emphasizes the importance of an exhaustive search for active tuberculosis in patients with erythema induratum, especially in countries where tuberculosis is prevalent, as the indiscriminate treatment of erythema induratum with steroids may be harmful. S254 posters miscellaneous i p291 erythema induratum of bazin s.
Poncets disease is a reactive arthritis that may accompany tuberculosis. Cases had no signs of active tb, but had a positive interferon. Vermutet wird eine hyperergische reaktion gegen mycobacterium tuberculosis. Erythema induratum of bazin and episcleritis in a 6 year. The existence of cutaneous nodules makes it necessary to perform a differential diagnosis between different clinical entities. Erythema induratum is an indolent eruption of illdefined nod ules affecting the backs of the lower legs of young or middle aged women. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. Disseminated erythema induratum of bazin springerlink.
Nov 15, 2019 in 1861, bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis. Computed tomography showed bilateral enlargement of the adrenal glands, with preserved outlines. Erythema induratum of bazin type associated with tb. Ortegalarrocea g, bobadilladelvalle m, poncedeleon a.
Zur kenntnis des erythema induratum bazin springerlink. She responded to att and the lesions started to resolve. Erythema induratum of bazin eib is a tuberculid, a condition occurring on the legs of female. We report erythema induratum in a patient who was found to have active endometrial tuberculosis. Eritema definicion, diagnostico, causas y tratamiento. Erythema induratum of bazin presenting as peripheral. Erythema induratum of bazin is a rare disease, characterized by the appearance of cutaneous erythema tous nodules, sometimes painful with frequent evolution to ulceration. John libbey eurotext european journal of dermatology.
We studied 101 skin biopsy specimens from 86 patients with clinicopathologic diagnosis of erythema induratum of bazin. Two cases of erythema induratum of bazin a rare cutaneous. Il decorso parallelo assunto dalla neoplasia e dall eritema indurato di bazin in questi 2 casi ci porta a formulare lipotesi che tale patologia possa talvolta manifestarsi come una sindrome paraneoplastica. Eritema induratum bazin pdf we describe two cases of erythema induratum of bazin eib, a cutaneous form of tb. We present a rare case of disseminated eib, in which igra was negative and. Full text is available as a scanned copy of the original print version. Vasculitis and zones of fat necrosis are absent in en and frequent in erythema induratum. Erythema induratum of bazin is a rare disease, characterized by the appearance of cutaneous. Il numero di segnalazioni di eritema indurato di bazin e in deciso calo in tutti i paesi piu sviluppati, verosimilmente in considerazione della minore incidenza della tubercolosi. The diagnosis can be difficult because tubercle bacilli are usually not found in smears or. We describe two cases of erythema induratum of bazin eib, a cutaneous form of tb. Home journals european journal of dermatology disseminated erythema induratum of bazin.
Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosis, and it was formerly thought to be always a reaction to the tuberculum bacillus. Get a printable copy pdf file of the complete article 905k, or click on a page image below to browse page by page. Nov 24, 2014 erythema induratum and nodular vasculitis had been seen as the same disease for many years but nodular vasculitis is now considered to be a multifactorial syndrome of lobular panniculitis in which tuberculosis may or may not be one of the various aetiologies. Clinically it has common features with diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. Pdf erythema induratum of bazin tuberculosis in disguise.
A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. Erythema induratum of bazin in a patient with postgraduate. A biopsy revealed changes consistent with nodular vasculitis. Links to pubmed are also available for selected references. Erythema induratum of bazin, nodular vasculitis histr. There has been a long controversy about the tuberculous cause of erythema induratum, a chronic form of nodular vasculitis. Diagnosis and treatment of erythema induratum bazin. A purified protein derivative and quantiferon test were positive, favoring the diagnosis of erythema induratum of bazin.
Erythema induratum of bazin, a chronic form of nodular vasculitis, may be associated with chronic infections by mycobacterium tuberculosis. Dermis erythema induratum bazin information on the diagnosis. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of tuberculid occurring on the legs, whereas nodular vasculitis represents the nontuberculous counterpart. Tuberculin skin tests are strongly positive in most cases. The clinical and histologic features of 26 cases of erythema induratum are. Erythema induratum of bazin victoria sharon md, heidi goodarzi md, cindy j chambers mph, maxwell a fung md, april w armstrong md dermatology online journal 16 4. Contributo allo studio delle alterazioni atrofiche regressive dell. A clinical and histopathological profile of patients with cutaneous tuberculosis. Erythema induratum of bazin eib is considered a tuberculide reaction and consists of recurrent painful nodules predominantly on the calves. Disseminated erythema induratum of bazin request pdf. Erythema induratum of bazin in a patient with endometrial tuberculosis. In 1861, bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis.
It is considered to be a hypersensitivity response to mycobacterium tuberculosis. However, it has been the practice for the last 50 years or so to recognize two variants one of presumptive tuberculous origin erythema induratum, bazintype and the other of nontuberculous origin, known as nodular vasculitis or erythema induratum, whitfieldtype. Peripheral neuropathy may manifest as a result of hypersensitivity reaction to tuberculousis antigens causing tissue and nerve damage in patients with erythema induratum of bazin eib. Erythema induratum of bazin associated with addisons. The skin lesions fitted the description of erythema induratum of bazin eib, one of a group of cutaneous hypersensitivity reactions to internal tuberculosis infection known as tuberculids. It occurs mainly in women, but it is very rare now. In 1945, montgomery et al, while fully acknowledging the existence of tuberculosisassociated erythema induratum, coined the term nodular vasculitis to describe chronic inflammatory nodules of the legs that s. Erythema induratum of bazin eib nodular vasculitis associated with. Erythema nodosum must be distinguished from erythema induratum and nodular vasculitis. Erythema induratum of bazin associated with addisons disease. Successful treatment of erythema induratum of bazin.
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